Moderna COVID vaccine safe, comparably effective in preschoolers ---clinical trial

Study: Moderna COVID vaccine safe, comparably effective in preschoolers The vaccine in kids 6 months to 5 years triggered similar immune response and protection as in young adults. CIDRAP

Two doses of the Moderna COVID-19 vaccine were safe in children aged 6 months to 5 years and triggered similar immune response and protection against infection as that seen in young adults, according to preliminary results from a phase 2/3 clinical trial published yesterday in the New England Journal of Medicine.

Emory University and Moderna researchers led the study, of which part 1 was an open-label trial to select the optimal Moderna mRNA-1273 vaccine dose, and part 2 was an observer-blinded, placebo-controlled evaluation of the selected dose in young children through Feb 21, 2022. The study took place during SARS-CoV-2 Omicron variant predominance.

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