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Antibodies spiked then waned after Pfizer, Moderna COVID vaccines, but J&J response was opposite

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One month after COVID-19 vaccination, compared with J&J recipients, nAB levels were 51 times higher among Moderna recipients and 21 times higher among Pfizer recipients. At 6 months, however, J&J vaccinees produced the same antibody response as that of Moderna and significantly higher concentrations than those of Pfizer.

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Bivalent COVID vaccine shows good Omicron protection while older version wanes --studies

Two studies published today measure the vaccine effectiveness (VE) of COVID-19 vaccines against laboratory-confirmed Omicron variant and subvariants and symptomatic disease. Vaccines that target the newer variants performed well, but primary vaccines offered rapidly waning protection from SARS-CoV-2 infections in the post-Omicron era.

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