Why protective antibodies fade after COVID-19 vaccines New findings could help explain why the immune protection generated by COVID-19 vaccines tends to decline over time. National Institutes of Health (NIH)

• Researchers found that current COVID-19 vaccines fail to generate mature and durable antibody-producing cells in the bone marrow.
• The findings could help explain why protection tends to decline over time.
• Better understanding of long-term immune responses could lead to improved vaccines that provide enduring protection.
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'Perfect storm' of distrust deepened inequalities during COVID-19 pandemic

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Research led by University of Manchester academics, examined the attitudes of people from minoritized ethnic groups, young adults and those with long-term physical and mental health conditions toward the COVID-19 vaccination program.

Researchers found that a "perfect storm" of marginalization and experience of structural inequalities led to distrust of the COVID-19 vaccination drive—and that marginalized communities felt "left behind" by policy and decision-makers prior to and during the pandemic.

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