In the third in a series of conflicting announcements about a Chinese-made COVID-19 vaccine candidate, Brazilian researchers reported today that the results of their efficacy trial were less impressive than they claimed last week. When analyzed by stricter criteria than used earlier, the vaccine’s efficacy against all forms of COVID-19, including mild cases, dropped from about 78% to 50%.
The vaccine still appeared to give nearly 100% protection against disease severe enough to require hospitalization, although the trial amassed too few of those cases for that result to reach statistical significance.
Commenting at the press conference today, microbiologist Natália Pasternak Taschner, president of the Question of Science Institute, a Brazilian nonprofit that aims to support public policy based on scientific evidence, said it was a “clear and clean study” and stressed that she wants th vaccine for herself and her parents. “We do not need to say this is the best vaccine in the world,” said Pasternak, who was not involved with the trial. “We have to say that this is our vaccine and it is a good vaccine to start the process of pandemic control.”
More than 4,400 people in the country died of the coronavirus on Tuesday, the day before lawmakers were set to charge President Trump with inciting last week’s violence at the Capitol.
Veteran virus trackers say they are chronicling something never before seen — the suppression of virtually every common respiratory and gastrointestinal virus besides the novel coronavirus. They theorize that is largely due to global shutdowns, mask-wearing and a host of other health protocols aimed at stemming the spread of the coronavirus.
These other viruses — including influenza A, influenza B, parainfluenza, norovirus, respiratory syncytial virus (RSV), human metapneumovirus — all appear to be circulating at or near levels lower than ever previously measured. The same is true for the respiratory bacteria that cause pertussis, better known as whooping cough, and pneumonia.
Growing up in the United States Virgin Islands, Dr. Marcella Nunez-Smith saw firsthand what can happen in a community with limited access to health care. Her father, Moleto “Bishop” Smith Sr., was only in his 40s when he suffered a debilitating stroke that left him partly paralyzed and with slurred speech.
The cause was high blood pressure, which could have been treated but had never been diagnosed. Without prompt access to advanced treatments, “the stroke was allowed to run its course,” Dr. Nunez-Smith, 45, recalled in a recent interview. Her father never fully recovered.
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